Peritoneal dialysis?related peritonitis as a risk factor for cardiovascular events

Background Cardiovascular disease is the leading cause of mortality in peritoneal dialysis (PD) patients. Infection known to increase risk cardiovascular events (CVE); however, no studies have examined association between PD peritonitis and CVE. Aim To examine as a factor for CVE Methods This retrospective cohort study included all adults undertaking ?3 months one Australian health district from 2001 2015. Baseline characteristics event information was obtained New Zealand Dialysis Transplant registry. The Centre Health Research Illawarra Shoalhaven Population facilitated data linkage using ICD10 coding capture information. Results A total 211 patients included, with median age 66 years (interquartile range 54.49–74.45); 64% were male. Peritonitis occurred 114 (54%) 65 (30.8%) experienced Identified factors included: cerebrovascular (hazard ratio (HR) 2.72, 95% confidence interval (CI) 1.36–5.47), diabetes (HR 2.41, CI 1.47–3.96), coronary artery 1.67, 1.01–2.77) 1.03, 1.01–1.06). There significant following 1.37, 0.81–2.32, P = 0.24), even when accounting age, disease, existing 1.32, 0.78–2.23, 0.30). Conclusions We did not find an episode result may be due small sample size or rapid treatment mitigating risk.